Barstar



Barstar (BST) is an inhibitor synthesized and secreted by the bacterium Bacillus amyloliquefaciens. It binds to the ribonuclease barnase (BA) very tightly and prevents it from digestion of the cell’s RNA.

3D Structures of Barstar
2hxx, 2cx6 – BST

1a19 – BST (mutant)

1l1k, 1bta, 1btb – BST – NMR

1ab7 - BST (mutant) - NMR

BST + BA
3da7 – BST + BA (mutant)

2za4, 1brs, 1bgs – BST + BA

1x1u, 1x1w, 1x1x, 1x1y, 1b27, 1b2u – BST (mutant) + BA

1b3s, 1b2s - BST (mutant) + BA (mutant)

1ay7 – BST + guanyl-specific RNase SA – Streptomyces aureofaciens